Hi RichardSa,

Note:For this sample i have refer below article for encrypt. For more details refer below article.

Encrypt data and store in Database in ASP.Net using C# and VB.Net

You need to pass VARCHAR(MAX) in your database for image.

SQL

CREATE TABLE [Encrypt_Image] 
(
     [Id] INT IDENTITY (1,1)
    ,[Name] VARCHAR(50)
    ,[Image] VARCHAR(MAX) Null
)
SELECT * FROM [Encrypt_Image]
DROP TABLE [Encrypt_Image]

HTML

<asp:FileUpload ID="FileUpload1" runat="server" />
<hr />
<asp:TextBox runat="server" ID="txtName"></asp:TextBox><br /><br />
<asp:Button ID="btnSubmit" runat="server" Text="Submit" OnClick="OnSubmit"></asp:Button>

Namespaces

C#

using System.IO;
using System.Data;
using System.Text;
using System.Data.SqlClient;
using System.Configuration;
using System.Security.Cryptography;

VB.Net

Imports System.IO
Imports System.Text
Imports System.Data
Imports System.Data.SqlClient
Imports System.Configuration
Imports System.Security.Cryptography

Code

C#

protected void OnSubmit(object sender, EventArgs e)
{
    string name = txtName.Text.Trim();
    byte[] image;
    using (BinaryReader br = new BinaryReader(FileUpload1.PostedFile.InputStream))
    {
        image = br.ReadBytes(FileUpload1.PostedFile.ContentLength);
    }
    string conString = ConfigurationManager.ConnectionStrings["constr"].ConnectionString;
    string query = "INSERT INTO Encrypt_Image (Name,Image) VALUES (@Name,@Image)";
    using (SqlConnection con = new SqlConnection(conString))
    {
        SqlCommand cmd = new SqlCommand(query);
        cmd.Parameters.AddWithValue("@Name", name);
        cmd.Parameters.AddWithValue("@image",this.Encrypt(Convert.ToBase64String(image)));
        cmd.Connection = con;
        con.Open();
        cmd.ExecuteNonQuery();
        con.Close();
    }
}
private string Encrypt(string clearText)
{
    string encryptionKey = "MAKV2SPBNI99212";
    byte[] clearBytes = Encoding.Unicode.GetBytes(clearText);
    using (Aes encryptor = Aes.Create())
    {
        Rfc2898DeriveBytes pdb = new Rfc2898DeriveBytes(encryptionKey, new byte[] { 0x49, 0x76, 0x61, 0x6e, 0x20, 0x4d, 0x65, 0x64, 0x76, 0x65, 0x64, 0x65, 0x76 });
        encryptor.Key = pdb.GetBytes(32);
        encryptor.IV = pdb.GetBytes(16);
        using (MemoryStream ms = new MemoryStream())
        {
            using (CryptoStream cs = new CryptoStream(ms, encryptor.CreateEncryptor(), CryptoStreamMode.Write))
            {
                cs.Write(clearBytes, 0, clearBytes.Length);
                cs.Close();
            }
            clearText = Convert.ToBase64String(ms.ToArray());
        }
    }
    return clearText;
}

VB.Net

Protected Sub OnSubmit(ByVal sender As Object, ByVal e As EventArgs)
    Dim name As String = txtName.Text.Trim()
    Dim image As Byte()
    Using br As BinaryReader = New BinaryReader(FileUpload1.PostedFile.InputStream)
        image = br.ReadBytes(FileUpload1.PostedFile.ContentLength)
    End Using
    Dim conString As String = ConfigurationManager.ConnectionStrings("constr").ConnectionString
    Dim query As String = "INSERT INTO Encrypt_Image (Name,Image) VALUES (@Name,@Image)"
    Using con As SqlConnection = New SqlConnection(conString)
        Dim cmd As SqlCommand = New SqlCommand(query)
        cmd.Parameters.AddWithValue("@Name", name)
        cmd.Parameters.AddWithValue("@image", Me.Encrypt(Convert.ToBase64String(image)))
        cmd.Connection = con
        con.Open()
        cmd.ExecuteNonQuery()
        con.Close()
    End Using
End Sub

Private Function Encrypt(ByVal clearText As String) As String
    Dim encryptionKey As String = "MAKV2SPBNI99212"
    Dim clearBytes As Byte() = Encoding.Unicode.GetBytes(clearText)
    Using encryptor As Aes = Aes.Create()
        Dim pdb As Rfc2898DeriveBytes = New Rfc2898DeriveBytes(encryptionKey, New Byte() {&H49, &H76, &H61, &H6E, &H20, &H4D, &H65, &H64, &H76, &H65, &H64, &H65, &H76})
        encryptor.Key = pdb.GetBytes(32)
        encryptor.IV = pdb.GetBytes(16)
        Using ms As MemoryStream = New MemoryStream()
            Using cs As CryptoStream = New CryptoStream(ms, encryptor.CreateEncryptor(), CryptoStreamMode.Write)
                cs.Write(clearBytes, 0, clearBytes.Length)
                cs.Close()
            End Using
            clearText = Convert.ToBase64String(ms.ToArray())
        End Using
    End Using
    Return clearText
End Function

Screenshot

Output