check this
HTML
Value: 1<asp:TextBox ID="TextBox1" runat="server"></asp:TextBox>
Value: 2<asp:TextBox ID="TextBox2" runat="server" OnTextChanged = "TextBox2_Changed" AutoPostBack = "true"></asp:TextBox>
Result:<asp:TextBox ID="TextBox3" runat="server"></asp:TextBox>
Code
protected void TextBox2_Changed(object sender, EventArgs e)
{
TextBox3.Text = (int.Parse(TextBox1.Text) * int.Parse(TextBox2.Text)).ToString();
}